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Myocardial necrosis produced in animals by means of crystalline streptococcal proteinase.

Abstract
Focal myocardial necrosis that was often extensive was found in a high percentage of rabbits, guinea pigs, and mice given a single intravenous injection of crystalline streptococcal proteinase. The findings are discussed in relation to their possible implications for the pathogenesis of the cardiac lesions of rheumatic fever.
AuthorsA KELLNER, T ROBERTSON
JournalThe Journal of experimental medicine (J Exp Med) Vol. 99 Issue 5 Pg. 495-503 (May 01 1954) ISSN: 0022-1007 [Print] United States
PMID13163324 (Publication Type: Journal Article)
Chemical References
  • Hydrolases
  • Endopeptidases
  • Peptide Hydrolases
  • Cysteine Endopeptidases
  • streptopain
Topics
  • Animals
  • Cysteine Endopeptidases
  • Disease
  • Endopeptidases
  • Guinea Pigs
  • Heart Diseases
  • Hydrolases
  • Mice
  • Myocardial Infarction
  • Myocardium
  • Necrosis
  • Peptide Hydrolases
  • Rabbits
  • Rheumatic Fever

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