Abstract |
The experiments on conscious rabbits have indicated that bonnecor given in doses of 0.05 mg/kg and 0.5 mg/kg accelerates clot formation and platelet aggregation, without changing the density of a thrombus. In experimental transient myocardial ischemia, the agent decreases the hypercoagulative change associated with the damaging effect of occlusion and reperfusion.
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Authors | S V Denisova, A V Sapozhkov |
Journal | Eksperimental'naia i klinicheskaia farmakologiia
(Eksp Klin Farmakol)
1992 Nov-Dec
Vol. 55
Issue 6
Pg. 29-31
ISSN: 0869-2092 [Print] Russia (Federation) |
Vernacular Title | Vliianie bonnekora na svertyvaemost' krovi i agregatsiiu trombotsitov v usloviiakh tranzitornoĭ ishemii miokarda. |
PMID | 1305870
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Anti-Arrhythmia Agents
- Dibenzazepines
- tiracizine
|
Topics |
- Animals
- Anti-Arrhythmia Agents
(pharmacology, therapeutic use)
- Blood Coagulation
(drug effects)
- Dibenzazepines
(pharmacology, therapeutic use)
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Female
- Male
- Myocardial Ischemia
(blood, drug therapy)
- Platelet Aggregation
(drug effects)
- Rabbits
- Time Factors
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