[The effect of the table salt substitute sanasol on arterial pressure, water-salt metabolism and kidney functions in experimental pathology of circulatory homeostasis].

Abstract

The potassium-containing salt substitute sanasol was examined for its effects on blood pressure and renal function in normo- and hypertensive rats, as well as on the edematous syndrome in circulatory insufficiency. The antihypertensive and occasional antiedematous effects of sanasol resulted in unfavorable changes in electrolyte balance. Sanasol was found to be ineffective in experimental renal failure.

• Authors: S Iu Shtrygol', T R Grishina
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) 1992 Nov-Dec Vol. 55 Issue 6 Pg. 21-4 ISSN: 0869-2092 [Print] Russia (Federation)
• Vernacular Title: Vliianie zamenitelia povarennoĭ soli sanasola na arterial'noe davlenie, vodno-solevoĭ obmen i funktsii pochek pri patologii tsirkuliatornogo gomeostaza v éksperimente.
• PMID: 1305867 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Potassium

Topics

• Animals
• Blood Circulation (drug effects)
• Blood Pressure (drug effects)
• Drug Evaluation, Preclinical
• Homeostasis (drug effects)
• Hypertension (drug therapy, physiopathology)
• Hypertension, Renovascular (drug therapy, physiopathology)
• Kidney (drug effects, physiopathology)
• Mice
• Potassium (pharmacology, therapeutic use)
• Rats
• Renal Insufficiency (drug therapy, physiopathology)
• Stress, Physiological (drug therapy, physiopathology)
• Water-Electrolyte Balance (drug effects)