[Pefloxacin in the treatment of chronic urinary infection].

Abstract

This study aimed at determining sensitivity of the hospital isolates to pefloxacin compared with other urinary antiseptics and assessment of its efficiency in the treatment of the chronic urinary infections. Disc diffusion technique was used to determine bacterial sensitivity to pefloxacin and other agents. Bacteria were isolated from the urine of the hospitalized patients. All tested strains were sensitive to pefloxacin. Its sensitivity exceeded in vitro 80%. Fifteen patients full sensitive to pefloxacin were treated. No bacteria were seen in the urine of 8 patients in two bacteriological cultures following the treatment, 3 patients stopped therapy due to adverse reactions, and no sterile urine was noted in 4 patients despite following a complete cycle of therapy.

• Authors: L Jeromin, M Sosnowski, W Dutkiewicz, W Kuligowski
• Journal: Polski tygodnik lekarski (Warsaw, Poland : 1960) (Pol Tyg Lek) 1992 Dec 7-14 Vol. 47 Issue 49-50 Pg. 1105-7 ISSN: 0032-3756 [Print] Poland
• Vernacular Title: Pefloksacyna w leczeniu przewlekłego zakazenia układu moczowego.
• PMID: 1305736 (Publication Type: English Abstract, Journal Article)

Chemical References

• Pefloxacin

Topics

• Chronic Disease
• Humans
• Microbial Sensitivity Tests
• Pefloxacin (therapeutic use)
• Urinary Tract Infections (drug therapy, microbiology, urine)