[Cetirizine for treating allergic seasonal rhinitis].

Abstract

In 14 persons suffering from allergic, seasonal rhinitis the efficacy of 14-days treatment of cetirizine (Zyrtec 10 mg/day) was evaluated. The study was performed in double blind randomised method. Cetirizine was significantly more effective than placebo in reducing the clinical symptoms of rhinitis near in 60% patients. The improvement of nasal mucosa state in laryngological investigation was observed in patients who were better clinically. The inhalatory challenge test with histamine in 9 patients was positive and after cetirizine treatment the bronchial hyperreactivity disappeared.

• Authors: I Grzelewska-Rzymowska, M Kalinowska-Graczyk, J Kopczyński, J Rozniecki
• Journal: Pneumonologia i alergologia polska (Pneumonol Alergol Pol) Vol. 60 Issue 11-12 Pg. 28-31 ( 1992) ISSN: 0867-7077 [Print] Poland
• Vernacular Title: Cetyryzyna w leczeniu alergicznego sezonowego niezytu nosa.
• PMID: 1303775 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Cetirizine

Topics

• Adolescent
• Adult
• Bronchial Provocation Tests
• Cetirizine (therapeutic use)
• Double-Blind Method
• Female
• Humans
• Male
• Nasal Mucosa (drug effects)
• Rhinitis, Allergic, Seasonal (diagnosis, drug therapy)