[The reaction of the T-immunity system in patients with malignant skin melanoma and stomach cancer to active nonspecific immunotherapy].

Abstract

Changes in E-receptor-bearing T-lymphocyte level (total and that of active T-lymphocytes) were studied in peripheral blood and resected material obtained from skin malignant melanoma and gastric cancer patients treated with rigvir, an original immunomodulator of the viral origin. Injection of rigvir into peripheral blood was followed by an increase in active T-lymphocyte level and stimulated their migration into tumor. The latter was determined by stage and rate of tumor advancement.

• Authors: L S Glinkina, R Zh Bruvere
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 38 Issue 6 Pg. 659-66 ( 1992) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Reaktsiia T-sistemy immuniteta bol'nykh zlokachestvennoĭ melanomoĭ kozhi i rakom zheludka na aktivnuiu nespetsificheskuiu immunoterapiiu.
• PMID: 1300766 (Publication Type: Journal Article)

Chemical References

• Adjuvants, Immunologic

Topics

• Adjuvants, Immunologic (therapeutic use)
• Drug Evaluation
• Enterovirus B, Human
• Humans
• Immunotherapy, Active
• Leukocyte Count
• Melanoma (immunology, pathology, therapy)
• Neoplasm Staging
• Rosette Formation
• Skin Neoplasms (immunology, pathology, therapy)
• Stomach Neoplasms (immunology, pathology, therapy)
• T-Lymphocytes (immunology)
• Time Factors