Fatty liver with elevated transaminase levels due to heterozygous apolipoprotein B deficiency.

Abstract

Elevation of transaminase levels in asymptomatic subjects could be due to a common benign condition such as fatty liver or a more serious disease such as chronic hepatitis due to various causes; in some subjects a liver biopsy is indicated. Heterozygous apolipoprotein B deficiency is an uncommon cause of transaminase elevation, as indicated by low levels of cholesterol and low density lipoprotein-cholesterol. This should be noted to avoid unnecessary investigations (including liver biopsy) in asymptomatic subjects with persistent elevation of transminase levels in the serum.

• Authors: T M Artekar, H G Desai
• Journal: Tropical gastroenterology : official journal of the Digestive Diseases Foundation (Trop Gastroenterol) 2003 Jan-Mar Vol. 24 Issue 1 Pg. 35-6 ISSN: 0250-636X [Print] India
• PMID: 12974215 (Publication Type: Case Reports, Journal Article)

Chemical References

• Apolipoproteins B
• Transaminases

Topics

• Adult
• Apolipoproteins B (deficiency)
• Fatty Liver (blood, diagnosis, etiology)
• Humans
• Liver (pathology)
• Male
• Transaminases (blood)