A rare cause of pituitary stalk enlargement and panhypopituitarism.

Abstract

Pituitary stalk involvement is seen in a variety of medical conditions such as infectious diseases, infiltrative diseases and tumors (intracranial and metastatic). Metastatic cancer has a greater propensity to involve the infundibulum and neurohypophysis. We report a case of a 68-year-old man who presented with thickening of the stalk, panhypopituitarism, diabetes insipidus and generalized lymphadenopathy. Lymphoma was diagnosed on axillary lymph node biopsy and lymphomatous involvement of the infundibulum was suspected. Although infundibular thickening resolved and diabetes insipidus improved after chemotherapy, panhypopituitarism persisted.

• Authors: Shehzad Basaria, Julie S Krop, Milena Braga-Basaria
• Journal: The Mount Sinai journal of medicine, New York (Mt Sinai J Med) Vol. 70 Issue 4 Pg. 265-7 (Sep 2003) ISSN: 0027-2507 [Print] United States
• PMID: 12968199 (Publication Type: Case Reports, Journal Article)

Topics

• Adenoma (complications, pathology)
• Aged
• Diabetes Insipidus (complications)
• Fatal Outcome
• Humans
• Hypopituitarism (etiology)
• Lymphoma, B-Cell (complications, pathology)
• Male
• Pituitary Gland (pathology)