| Abstract | A 36-year-old male patient suffered from therapy resistant sarcoidosis with long-standing contractures, myopathy, skin lesions and pulmonary changes. Low-dose therapy with thalidomide (50 mg/day) was well tolerated, and the patient rapidly improved. Thalidomide was effective for muscular, cutaneous, and pulmonary involvement in our patient. This is the first report on the efficacy of thalidomide in muscle sarcoidosis. Therefore, thalidomide may become a second-line agent in patients with severe muscle and skin involvement, but further studies are warranted. |
| Authors | M C Walter, H Lochmüller, B Schlotter-Weigel, T Meindl, W Müller-Felber
(Affiliation: Friedrich-Baur-Institute, Department of Neurology, Ludwig-Maximilians University of Munich, Ziemssenstr. 1a, 80336 Munich, Germany. Maggie.Walter at lrz.uni-muenchen.de)
|
| Journal | Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology / edited by the Gaetano Conte Academy for the study of striated muscle diseases
(Acta Myol)
Vol. 22
Issue 1
Pg. 22-5
(May 2003)
ISSN: 1128-2460 Italy |
| PMID | 12966701
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Immunosuppressive Agents
- Thalidomide
|
| Topics |
- Adult
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Magnetic Resonance Imaging
- Male
- Muscular Diseases
(drug therapy, pathology)
- Sarcoidosis
(drug therapy, pathology)
- Thalidomide
(therapeutic use)
|
