[Cutaneous xanthomas associated with minocycline-induced cholestatic jaundice].

Abstract

Minocycline is an effective treatment of acne vulgaris, especially for inflammatory forms. Prescription rates have increased in recent years accompanied by a number of reports concerning drug-induced side effects. An otherwise healthy woman developed an erythema multiform-like rash and and toxic hepatic damage causing cholestatic jaundice following long-term minocycline use. Unusual cutaneous lipid deposition also developed. Minocycline-induced side effects are reviewed.

• Authors: C Bamberg, J Laskowski, R Zimmermann, G Gross
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 54 Issue 9 Pg. 864-8 (Sep 2003) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Xanthomatose der Haut bei cholestatischem Ikterus nach Minocyclin-Langzeittherapie.
• PMID: 12955265 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Minocycline

Topics

• Acne Vulgaris (drug therapy)
• Adult
• Anti-Bacterial Agents (administration & dosage, adverse effects, therapeutic use)
• Biopsy
• Erythema Multiforme (diagnosis, pathology)
• Female
• Follow-Up Studies
• Humans
• Jaundice, Obstructive (chemically induced, diagnosis, pathology)
• Liver (pathology)
• Minocycline (administration & dosage, adverse effects, therapeutic use)
• Skin (pathology)
• Time Factors
• Xanthomatosis (diagnosis, pathology)