Abstract |
The sulfonated phthalimidomethyl phthalocyanine hydroxyl aluminum ( Al(OH)PcSP) is an amphiphilic photosensitizer which was proved to have the photodynamic activities against cancer. The electronic absorption spectra and aggregation state of the Al(OH)PcSP in aqueous alcoholic solutions and water were investigated. The results showed that the Al(OH)PcSP existed in the form of monomer in aqueous alcoholic solutions. The increase in the carbon chain and hydroxy of alcohol in solutions had no significant effects on the absorption spectra behaviors of Al(OH)PcSP. But in water, the Al(OH)PcSP existed in the equilibrium between monomer and dimer. The dimerization constant was 5.7307 x 10(4) mol-1.L. The characteristic absorption peak of the Q band of the Al(OH)PcSP dimer was red shifted to 740.5 nm from that of the monomer (676.5 nm), which contrast with those of other metal phthalocyanines dimer. The study on the fluorescence spectra of Al(OH)PcSP in aqueous alcoholic solutions suggested that the fluorescence of the dimer was weak.
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Authors | J Huang, E Liu, Z Dai, C Shen, S Yang, N Chen, J Huang |
Journal | Guang pu xue yu guang pu fen xi = Guang pu
(Guang Pu Xue Yu Guang Pu Fen Xi)
Vol. 20
Issue 5
Pg. 673-6
(Oct 2000)
ISSN: 1000-0593 [Print] China |
PMID | 12945414
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Indoles
- Organometallic Compounds
- Photosensitizing Agents
- Phthalimides
- Solutions
- Sulfonic Acids
- sulfonated phthalimidomethyl phthalocyanine hydroxyl aluminum
- aluminum tetrasulfophthalocyanine
- aluminum phthalocyanine disulfonate
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Topics |
- Electron Probe Microanalysis
- Indoles
(chemistry)
- Kinetics
- Organometallic Compounds
(chemistry)
- Photosensitizing Agents
(chemistry)
- Phthalimides
(metabolism, pharmacology)
- Solutions
- Spectrometry, Fluorescence
- Spectrophotometry, Atomic
- Structure-Activity Relationship
- Sulfonic Acids
(chemistry)
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