Abstract | OBJECTIVE: STUDY DESIGN:
Hepatocyte growth factor levels were measured in 42 plasma samples between weeks 14 and 21 of gestation using an enzyme-linked immunosorbent assay (ELISA). Results were correlated to pregnancy outcome and Mann-Whitney U-test applied to study the differences. RESULTS:
Hepatocyte growth factor values in pregnancies that develop preeclampsia (n=12) were not significantly different from unaffected pregnancies (n=21, multiples of the median (MoM)=1.38, P=0.47). However, hepatocyte growth factor values were significantly elevated in pregnancies of small-for-gestational age (SGA) fetuses (n=9) compared to uncomplicated pregnancies (MoM=2.66, P<0.001). CONCLUSION:
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Authors | May Lee Tjoa, Monique A M Mulders, John M G van Vugt, Marinus A Blankenstein, Cees B M Oudejans, Inge J van Wijk |
Journal | European journal of obstetrics, gynecology, and reproductive biology
(Eur J Obstet Gynecol Reprod Biol)
Vol. 110
Issue 1
Pg. 20-5
(Sep 10 2003)
ISSN: 0301-2115 [Print] Ireland |
PMID | 12932865
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers
- Hepatocyte Growth Factor
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Topics |
- Biomarkers
(blood)
- Enzyme-Linked Immunosorbent Assay
- Female
- Gestational Age
- Hepatocyte Growth Factor
(blood)
- Humans
- Infant, Newborn
- Infant, Small for Gestational Age
- Pre-Eclampsia
(blood, diagnosis)
- Pregnancy
- Pregnancy Outcome
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