[The effect of semen antisperm antibody on human sperm acrosin activity].

Abstract

OBJECTIVES:

To study the effect of antisperm antibody(AsAb) on human sperm acrosin activity.

METHODS:

AsAb and sperm acrosin activity were measured and analyzed in 3,432 infertile men and 65 fertile volunteers.

RESULTS:

AsAb positive rate was 10.20% in 3,432 case of male infertility, and 9.37% in 2,882 infertile males who received tests of sperm acrosin activity. Acrosin activity of infertility cases were lower than those of fertile cases(P < 0.001). The comparison between AsAb positive group and AsAb negative group infertility cases showed no significant differences of acrosin activity (P > 0.05). Between normal acrosin activity group and abnormal acrosin activity group, there was no significant difference of AsAb positive rate (P > 0.05).

CONCLUSIONS:

Antisperm antibody could not affect acrosin activity.

• Authors: Rui-Zhi Liu, Ying-Li Lu, Zong-Ge Xu, Wen-Jing Zuo, Ji-Li Xin, Zhong-Shan Wang
• Journal: Zhonghua nan ke xue = National journal of andrology (Zhonghua Nan Ke Xue) Vol. 9 Issue 4 Pg. 252-3 ( 2003) ISSN: 1009-3591 [Print] China
• PMID: 12931362 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Autoantibodies
• Acrosin

Topics

• Acrosin (metabolism)
• Adult
• Autoantibodies (analysis)
• Case-Control Studies
• Humans
• Infertility, Male (immunology)
• Male
• Semen (chemistry)
• Spermatozoa (enzymology, immunology)