Abstract | PURPOSE: PATIENTS AND METHODS: Ga and/or bone scintigraphy was performed for 123 patients with primary squamous cell carcinoma (SCC). Abnormal accumulation sites detected with scintigraphy were reevaluated with radiography or computed tomography. Whether the accumulation sites were metastatic was determined according to the radiographic findings and the later clinical course of the patients. RESULTS: Ga scintigraphy did not detect distant metastases or 4 synchronous cancers at other sites and provided no useful information on the emergence of delayed pulmonary metastases that developed in 3 cases after a few months. Ga scintigraphy showed an abnormal accumulation in 53% of primary tumors and 25% of metastatic cervical lymph nodes, and the detection of accumulation was closely related to the size of the lesion. Bone scintigraphy showed 1 case (0.9%) with distant metastasis to the vertebra; however, there were numerous false-positive cases that required additional radiographic confirmation. CONCLUSIONS: These results suggested that Ga and bone scintigraphy at the initial examination of patients with primary oral SCC are ineffective for detecting distant metastasis and other malignancies because of the low incidence of these lesions and the diagnostic inaccuracy of scintigraphy.
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Authors | Kojiro Onizawa, Hiroshi Yoshida |
Journal | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
(J Oral Maxillofac Surg)
Vol. 61
Issue 8
Pg. 913-7
(Aug 2003)
ISSN: 0278-2391 [Print] United States |
PMID | 12905444
(Publication Type: Journal Article)
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Chemical References |
- Citrates
- Gallium Radioisotopes
- Radiopharmaceuticals
- Gallium
- gallium citrate
- Technetium Tc 99m Medronate
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Bone Neoplasms
(diagnostic imaging, secondary)
- Carcinoma, Squamous Cell
(diagnostic imaging)
- Citrates
- Female
- Follow-Up Studies
- Gallium
- Gallium Radioisotopes
- Humans
- Lymphatic Metastasis
(diagnostic imaging)
- Male
- Middle Aged
- Mouth Neoplasms
(diagnostic imaging)
- Neck
(diagnostic imaging)
- Neoplasm Staging
- Neoplasms, Multiple Primary
(diagnostic imaging)
- Radionuclide Imaging
- Radiopharmaceuticals
- Technetium Tc 99m Medronate
- Tomography, X-Ray Computed
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