[Clinical evaluation of cefprozil granules in pediatric field].

Abstract

Cefprozil (CFPZ, BMY-28100) granules were administered to 20 children with bacterial infections: acute tonsillitis 8, acute bronchitis 10, purulent lymphadenitis 1, urinary tract infection 1. Daily doses ranged 29-50 mg/kg. The drug was given orally, 3 times a day and the durations of administration were 5 to 9 days. Clinical efficacies were excellent in 16 cases and good in 4 cases, hence the overall efficacy rate was 100%. No side effects were observed in any of these cases. As for abnormal laboratory test values, thrombocytosis was observed in 1 case. From the above results, we consider CFPZ granules to be a useful drug for the treatment of pediatric patients with various bacterial infections.

• Authors: S Furukawa, T Okada
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 45 Issue 12 Pg. 1658-62 (Dec 1992) ISSN: 0368-2781 [Print] Japan
• PMID: 1289584 (Publication Type: Journal Article)

Chemical References

• Cephalosporins
• cefprozil

Topics

• Administration, Oral
• Age Factors
• Bacteria (isolation & purification)
• Bacterial Infections (drug therapy, microbiology)
• Cephalosporins (administration & dosage, adverse effects, therapeutic use)
• Child
• Child, Preschool
• Drug Evaluation
• Female
• Humans
• Infant
• Male
• Thrombocytosis (chemically induced)