Toxoplasmosis transmitted to a newborn from the mother infected 20 years earlier.

Abstract

PURPOSE:

To present a case of congenital toxoplasmosis in a newborn whose mother had a 20-year history of a chorioretinal macular scar and positive serology for toxoplasmosis.

DESIGN/METHODS:

Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newborn who presented with a focal necrotizing retinochoroiditis characteristic of toxoplasmosis, as well as positive immunoglobulin (Ig) G and M serology for toxoplasmosis. The workup was negative for other entities.

CONCLUSION:

This case suggests that women with old retinal scars due to toxoplasmosis and long-standing IgG antibodies to toxoplasmosis are also at risk of transmitting this disease to the fetus.

• Authors: Claudio Silveira, Rosane Ferreira, Cristina Muccioli, Robert Nussenblatt, Rubens Belfort Jr
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 136 Issue 2 Pg. 370-1 (Aug 2003) ISSN: 0002-9394 [Print] United States
• PMID: 12888070 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Protozoan
• Immunoglobulin G
• Immunoglobulin M
• Sulfadiazine
• Pyrimethamine

Topics

• Adult
• Animals
• Antibodies, Protozoan (blood)
• Drug Therapy, Combination
• Enzyme-Linked Immunosorbent Assay
• Female
• Humans
• Immunoglobulin G (analysis)
• Immunoglobulin M (analysis)
• Infant, Newborn
• Infectious Disease Transmission, Vertical
• Male
• Pregnancy
• Pregnancy Complications, Parasitic (diagnosis, drug therapy, parasitology)
• Pyrimethamine (therapeutic use)
• Retinal Necrosis Syndrome, Acute (diagnosis, drug therapy, parasitology)
• Sulfadiazine (therapeutic use)
• Toxoplasma (immunology)
• Toxoplasmosis, Congenital (diagnosis, drug therapy, transmission)
• Toxoplasmosis, Ocular (diagnosis, drug therapy, transmission)