[Cervico-mediastinal hematoma secondary to extracapsular hemorrhage of parathyroid carcinoma. Clinical case and review of the literature].

Abstract

Extracapsular parathyroid haemorrhage is a rare but ominous occurrence, which may cause cervico-mediastinal haematoma and a severe calcaemia imbalance. We identified only 23 cases reported in the literature and these were always secondary to adenoma, hyperplasia or cysts, and never to carcinoma. We describe a case of a 56-year-old man who was admitted to our Institute because of the sudden development of an anterior neck swelling, together with dysphagia, dyspnoea and hoarseness. Physical examination revealed a large ecchymosis extending from the anterior neck to the upper chest, while the early symptoms had disappeared. Laboratory studies, ultrasonography and 99mtTC-Sestamibi scintiscan demonstrated the presence of primary parathyroidism due to a right inferior parathyroid neoplasm. At operation, the parathyroid was excised en bloc with the right thyroid lobe because they were joined together by an extensive fibrous reaction. Histological examination showed a well-differentiated parathyroid carcinoma with evidence of recent haemorrhage. To the best of our knowledge this is the first case of extracapsular haemorrhage due to a parathyroid carcinoma. In summary, although parathyroid haemorrhage is a rare condition, it should always be suspected when a painful mass or diffuse swelling suddenly occurs in the anterior neck, with or without ecchymosis, especially when serum calcium and phosphorus are abnormal.

• Authors: Enrico Erdas, Sergio Licheri, Maria Letizia Lai, Giuseppe Pisano, Mariano Pomata, Giovanni Maria Daniele
• Journal: Chirurgia italiana (Chir Ital) 2003 May-Jun Vol. 55 Issue 3 Pg. 425-34 ISSN: 0009-4773 [Print] Italy
• Vernacular Title: Ematoma cervico-mediastinico secondario ad emorragia extracapsulare di carcinoma paratiroideo. Caso clinico e revisione della letteratura.
• PMID: 12872580 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Topics

• Carcinoma, Papillary (complications)
• Hematoma (etiology)
• Humans
• Male
• Mediastinal Diseases (etiology)
• Middle Aged
• Neck
• Parathyroid Neoplasms (complications)