Urodynamic and clinical evaluation of postmenopausal women with stress urinary incontinence before and after cyclic estrogen therapy.

Abstract

OBJECTIVE:

The purpose [corrected] of this study was to evaluate the effects of isolated cyclic estrogen therapy in menopausal women with stress urinary incontinence, and thus without the effects of progesterone.

METHODS:

Nineteen menopausal patients with stress urinary incontinence were selected and submitted to anamnesis and physical, gynecological and urodynamic examinations. The group was homogeneous in relation to parity, body mass index and degree of urogenital prolapse. All the patients received conjugated equine estrogens orally, at a dose of 0.625 mg, for 21 days each month. After three months the clinical and urodynamic evaluations in relation to urine loss, were performed again.

RESULTS:

Of the patients 57.9% were satisfied with the treatment. The urodynamic parameters remained unaltered in 36.85% of the patients.

CONCLUSION:

Our results show that estrogen is important for stress urinary incontinence in postmenopause, specially in patients without cystocele or with cystocele of degree I or II.

• Authors: V R V Góes, M G F Sartori, E C Baracat, G Rodrigues de Lima, M J B C Girão
• Journal: Clinical and experimental obstetrics & gynecology (Clin Exp Obstet Gynecol) Vol. 30 Issue 2-3 Pg. 103-6 ( 2003) ISSN: 0390-6663 [Print] Singapore
• PMID: 12854853 (Publication Type: Journal Article)

Chemical References

• Estrogens, Conjugated (USP)

Topics

• Estrogen Replacement Therapy
• Estrogens, Conjugated (USP) (administration & dosage)
• Postmenopause
• Treatment Outcome
• Urinary Incontinence, Stress (drug therapy, physiopathology)
• Urodynamics