Schinzel-Giedion syndrome with sacrococcygeal teratoma.

Abstract

A case of Schinzel-Giedion syndrome, a rare malformation syndrome, is described. In addition to the classic features of the syndrome, the patient had a malignant sacrococcygeal teratoma and agenesis of the corpus callosum. So far, this patient is the fifth case with a sacrococcygeal tumor and the eighth with anomalies of the corpus callosum. According to this occurrence of uncommon tumors, risk of malignancy could be a component of Schinzel-Giedion syndrome.

• Authors: Alessandro Sandri, Andrea Domenco Manazza, Daniele Bertin, Margherita Silengo, Maria Eleonora Basso, Marco Forni, Enrico Madon
• Journal: Journal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 25 Issue 7 Pg. 558-61 (Jul 2003) ISSN: 1077-4114 [Print] United States
• PMID: 12847324 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• alpha-Fetoproteins

Topics

• Abnormalities, Multiple (diagnosis, pathology)
• Endodermal Sinus Tumor (pathology, surgery)
• Fatal Outcome
• Female
• Humans
• Infant
• Male
• Sacrococcygeal Region
• Teratoma (diagnosis, pathology, surgery)
• alpha-Fetoproteins (analysis)