[Effect of leukocyte depleting polyester filters on thrombocytapheresis concentrates].

Abstract

We studied platelet loss, leukocyte depletion, T/B cell ratio, platelet morphology and platelet function (aggregation, hypotonic shock reaction, retention and retraction) prior to and after filtration through two different polyester filters (Sepacell PL-5A, Pall PL100) as well as the posttransfusional platelet increment 1 h after transfusion in 8 pairs of single-donor platelet concentrates (Cobe Spectra, Fresenius AS 104). Leukocyte depletion was effective (>99.9%) and platelet loss acceptable in both filters, all tests showing no indication of a diminished platelet function by filtration.

• Authors: V Weisbach, H Riess, N Gindi, S Serke, T Zeiler, M Riewald, J Zingsem, R Eckstein
• Journal: Beitrage zur Infusionstherapie = Contributions to infusion therapy (Beitr Infusionsther) Vol. 30 Pg. 170-3 ( 1992) ISSN: 1011-6974 [Print] Switzerland
• Vernacular Title: Der Einfluss leukozytendepletierender Polyesterfilter auf Thrombozytapheresekonzentrate.
• PMID: 1284699 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Polyesters

Topics

• Blood Component Transfusion (instrumentation)
• Blood Preservation (instrumentation)
• Humans
• Leukocyte Count
• Lymphocyte Depletion (instrumentation)
• Lymphocyte Subsets (cytology)
• Platelet Count
• Platelet Function Tests
• Plateletpheresis (instrumentation)
• Polyesters
• Ultrafiltration (instrumentation)