Production and resolution of cantharidin-induced inflammatory blisters.

Abstract

While inflammatory blisters have long been utilized as a means of evaluating antimicrobial disposition to aid in the development of new treatments for skin and skin structure infections, sparse data are available regarding the healing of the blisters once the experiment has been completed. We report the blister induction technique and resolution time in ten volunteers enrolled in a pharmacokinetic study using the cantharidin-induced inflammatory blister technique.

• Authors: Dana Maglio, Charles H Nightingale, David P Nicolau
• Journal: International journal of antimicrobial agents (Int J Antimicrob Agents) Vol. 22 Issue 1 Pg. 77-80 (Jul 2003) ISSN: 0924-8579 [Print] Netherlands
• PMID: 12842333 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Irritants
• Cantharidin

Topics

• Anti-Bacterial Agents (pharmacokinetics)
• Blister (chemically induced, metabolism, pathology)
• Cantharidin (administration & dosage, toxicity)
• Humans
• Inflammation (chemically induced, metabolism, pathology)
• Irritants (administration & dosage, toxicity)
• Skin (metabolism, pathology)
• Skin Pigmentation
• Time Factors
• Wound Healing