Abstract | BACKGROUND:
Leukoaraiosis, a term that defines an abnormal appearance of the subcortical white matter of the brain on neuroimaging (bilateral patchy or diffuse areas of low attenuation on CT or hyperintense T2 MR areas), has gained evidence in retrospective studies to demonstrate its association with stroke and in prospective studies to demonstrate its prognostic value related to the occurrence of stroke, both ischemic and hemorrhagic, or the occurrence of vascular death. SUMMARY OF REVIEW: CONCLUSIONS:
Leukoaraiosis shares with stroke common pathophysiological mechanisms and, because it is likely an expression of the same disease, must be regarded as an intermediate surrogate of stroke rather than a true stroke risk factor.
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Authors | Domenico Inzitari |
Journal | Stroke
(Stroke)
Vol. 34
Issue 8
Pg. 2067-71
(Aug 2003)
ISSN: 1524-4628 [Electronic] United States |
PMID | 12829859
(Publication Type: Journal Article, Review)
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Topics |
- Brain
(blood supply, diagnostic imaging, pathology)
- Brain Infarction
(etiology)
- Cerebral Hemorrhage
(etiology)
- Cerebrovascular Disorders
(complications, diagnosis)
- Humans
- Magnetic Resonance Imaging
- Microcirculation
(diagnostic imaging, pathology)
- Predictive Value of Tests
- Risk Factors
- Stroke
(etiology)
- Tomography, X-Ray Computed
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