[Two cases of mineralocorticoids deficiency as first endocrine manifestation of APECED syndrome].

Abstract

The Authors report two cases of APECED syndrome (Auto-immune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy) revealed by hyponatremia due to isolated mineralocorticoids deficiency. Such cases illustrate the variable endocrine features revealing the syndrome. The mechanisms underlying the auto-immune destruction of the adrenals are discussed.

• Authors: P Barat, M Joussein, J C Carel
• Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie (Arch Pediatr) Vol. 10 Issue 2 Pg. 137-9 (Feb 2003) ISSN: 0929-693X [Print] France
• Vernacular Title: A propos de deux cas de déficit en minéralo-corticoïdes dû à une première manifestation endocrinienne du syndrome APECED.
• PMID: 12829356 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Mineralocorticoids

Topics

• Adrenal Glands (pathology, physiology)
• Child, Preschool
• Humans
• Hyponatremia (etiology, pathology)
• Male
• Mineralocorticoids (deficiency)
• Polyendocrinopathies, Autoimmune (complications, diagnosis)