Abstract | UNLABELLED: OBJECTIVE: METHODS: Among 311 patients who underwent heart transplantation in our hospital, five (2%) had end-stage cardiomyopathies related to inherited myopathies. Four patients had muscular dystrophy (three Becker's muscular dystrophy and one hips-dystrophy) and the fifth desminopathy. In one patient cardiomyopathy was the initial manifestation of the disease. Mean age at the time of transplantation was 38.6 years (range from 24 to 55). The mean follow-up after transplantation was 57.4 months (range from 13 to 128). The intraoperative and postoperative course of these individuals did not show higher complication rates than other patients. All recipients experienced successful rehabilitation; no evidence of graft dysfunction has been detected during follow-up. All of them are alive with a good performance status. CONCLUSIONS: In our experience, patients who underwent heart transplantation due to end-stage cardiomyopathy secondary to inherited myopathy with only a mild degree of muscle impairment did not display higher postoperative nor long-term complications compared to other recipients.
|
Authors | M J Ruiz-Cano, J F Delgado, C Jiménez, S Jiménez, L Cea-Calvo, V Sánchez, P Escribano, M A Gómez, L Gil-Fraguas, C Sáenz de la Calzada |
Journal | Transplantation proceedings
(Transplant Proc)
Vol. 35
Issue 4
Pg. 1513-5
(Jun 2003)
ISSN: 0041-1345 [Print] United States |
PMID | 12826208
(Publication Type: Case Reports, Journal Article)
|
Topics |
- Adolescent
- Adult
- Cardiomyopathies
(etiology, surgery)
- Follow-Up Studies
- Heart Transplantation
- Humans
- Male
- Middle Aged
- Muscular Dystrophies
(complications)
- Muscular Dystrophy, Duchenne
(surgery)
- Retrospective Studies
- Time Factors
- Treatment Outcome
|