Abstract | BACKGROUND: In patients with complete bile duct obstruction, the only pathway of bile acid elimination is through the urine. However, the urinary excretion of various bile acid conjugates in the presence of bile duct obstruction has not been clarified. Given this factor, the urinary excretion of various bile acids was compared in rats that were bile duct-ligated for 3 days. METHODS: After urinary bladder cannulation, radiolabeled bile acids were intravenously injected, and urine samples were collected every 2 h for 6 h, and radioactivity was counted. RESULTS: CONCLUSIONS:
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Authors | Yukiko Takada, Naoyo Sano, Hajime Takikawa |
Journal | Journal of gastroenterology
(J Gastroenterol)
Vol. 38
Issue 6
Pg. 561-6
( 2003)
ISSN: 0944-1174 [Print] Japan |
PMID | 12825132
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Bile Acids and Salts
- Carbon Radioisotopes
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Topics |
- Animals
- Bile Acids and Salts
(urine)
- Carbon Radioisotopes
- Cholestasis
(urine)
- Chromatography, Thin Layer
- Common Bile Duct
(surgery)
- Common Bile Duct Diseases
(urine)
- Ligation
- Liver
(metabolism)
- Male
- Rats
- Rats, Sprague-Dawley
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