Abstract | INTRODUCTION: CASE REPORT: A 40-year-old man presented with haematemesis after ingestion of 1 g mercuric sulphate and rapidly deteriorated in the emergency department, requiring intubation and ventilation. His initial blood mercury was 15 580 microg/l. At 4.5 hours after ingestion he was started on DMPS. He rapidly developed acute renal failure and so he was started on CVVHDF for renal support and in an attempt to improve mercury clearance; CVVHDF was continued for 14 days. METHODS: Regular ultradialysate and pre- and post-filtrate blood samples were taken and in addition all ultradialysate generated was collected to determine its mercury content. RESULTS: The total amount of mercury in the ultrafiltrate was 127 mg (12.7% of the ingested dose). The sieving coefficient ranged from 0.13 at 30-hours to 0.02 at 210-hours after ingestion. He developed no neurological features and was discharged from hospital on day 50. Five months after discharge from hospital he remained asymptomatic, with normal creatinine clearance. DISCUSSION: CONCLUSION:
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Authors | Paul I Dargan, Lucy J Giles, Craig I Wallace, Ivan M House, Alison H Thomson, Richard J Beale, Alison L Jones |
Journal | Critical care (London, England)
(Crit Care)
Vol. 7
Issue 3
Pg. R1-6
(Jun 2003)
ISSN: 1364-8535 [Print] England |
PMID | 12793883
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Mercury Compounds
- Sulfates
- Unithiol
- mercuric sulfate
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Topics |
- Acute Kidney Injury
(chemically induced, therapy)
- Adult
- Follow-Up Studies
- Gastritis
(chemically induced, therapy)
- Hematemesis
(chemically induced, therapy)
- Hemodiafiltration
(methods)
- Humans
- Male
- Mercury Compounds
(pharmacokinetics, poisoning)
- Mercury Poisoning
(therapy)
- Metabolic Clearance Rate
- Stomach Ulcer
(chemically induced, therapy)
- Suicide, Attempted
- Sulfates
(pharmacokinetics, poisoning)
- Treatment Outcome
- Unithiol
(therapeutic use)
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