| Abstract | BACKGROUND: Sex differences in the response threshold to painful stimuli and the higher number of chronic pain syndromes in women than in men have prompted a series of studies on lower animals and humans aimed at clarifying the role of gonadal hormones in pain. OBJECTIVE: This article examines the morphologic and functional aspects of gonadal hormone systems and the relations between gonadal hormones and pain circuits, to identify areas deserving of increased attention in elucidating the endocrine mechanisms that contribute to abnormal pain states. |
| Authors | Anna Maria Aloisi
(Affiliation: Department of Physiology, University of Sienna, Italy. aloisi at unisi.it)
|
| Journal | The Clinical journal of pain
(Clin J Pain)
2003 May-Jun
Vol. 19
Issue 3
Pg. 168-74
ISSN: 0749-8047 United States |
| PMID | 12792555
(Publication Type: Journal Article, Review)
|
| Chemical References |
- Androgens
- Estrogens
- Gonadal Steroid Hormones
|
| Topics |
- Aging
(physiology)
- Androgens
(metabolism)
- Animals
- Central Nervous System
(physiopathology)
- Estrogens
(metabolism)
- Female
- Gonadal Steroid Hormones
(metabolism)
- Gonads
(physiopathology)
- Humans
- Male
- Pain
(physiopathology)
- Pain Threshold
(physiology)
- Sex Characteristics
- Sex Differentiation
(physiology)
|
