Abstract | OBJECTIVE: DATA SOURCES: STUDY SELECTION: We selected articles based on whether the cases described appeared to fit the description of the entity autoimmune progesterone dermatitis. All cases included had dermatologic reactions occurring during the luteal phase of the menstrual period, positive skin or intramuscular reactions to progesterone, and treatment amenable to anovulatory agents and/or hysterectomy with bilateral salpingo-oophorectomy. RESULTS: We found approximately 50 published cases of autoimmune progesterone dermatitis, and only nine known cases of its manifestation as anaphylaxis. These cases, including the case described by us, are summarized, and successful diagnostic and therapeutic approaches in the literature are reviewed. CONCLUSIONS:
Autoimmune progesterone dermatitis is a rare entity associated with progesterone production of the luteal phase of a woman's menstrual cycle. It can be diagnosed using intradermal or intramuscular progesterone tests and can be treated by disrupting the ovulation cycle using specific medications or by oopherectomy.
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Authors | Joy L Snyder, Guha Krishnaswamy |
Journal | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
(Ann Allergy Asthma Immunol)
Vol. 90
Issue 5
Pg. 469-77; quiz 477, 571
(May 2003)
ISSN: 1081-1206 [Print] United States |
PMID | 12775127
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
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Topics |
- Adult
- Anaphylaxis
(etiology, immunology, therapy)
- Autoimmune Diseases
(etiology, immunology, therapy)
- Female
- Humans
- Menstrual Cycle
(immunology)
- Progesterone
(immunology)
- Urticaria
(etiology, immunology, therapy)
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