[Hemodynamics and cell membrane effects of angiotensin II receptor antagonists in treatment of hypertension].

Abstract

Strain on calcium-dependent mechanisms in essential hypertension (EH) is in activation of the calcium pump, structural-and-functional changes in Ca2+ ATPase and activation of proteinase C. In EH patients presenting with a high sensitivity to angiotensin II, there comes to be frequently seen an insufficient effectiveness of antagonists of receptors to angiotensin II.

• Authors: V D Babadzhan
• Journal: Likars'ka sprava (Lik Sprava) Issue 2 Pg. 20-4 ( 2003) ISSN: 1019-5297 [Print] Ukraine
• Vernacular Title: Gemodinamicheskie i membrannokletochnye éffekty antagonistov retseptorov k angiotenzinu II pri lechenii gipertonicheskoĭ bolezni.
• PMID: 12774467 (Publication Type: English Abstract, Journal Article)

Chemical References

• Angiotensin Receptor Antagonists
• Antihypertensive Agents
• Membrane Proteins
• Hydrochlorothiazide
• Angiotensin II
• Peptidyl-Dipeptidase A
• Adenosine Triphosphatases
• Losartan
• Calcium

Topics

• Adenosine Triphosphatases (metabolism)
• Adult
• Angiotensin II (blood)
• Angiotensin Receptor Antagonists
• Antihypertensive Agents (therapeutic use)
• Blood Platelets (metabolism)
• Calcium (metabolism)
• Erythrocytes (enzymology, metabolism)
• Hemodynamics (drug effects, physiology)
• Humans
• Hydrochlorothiazide (therapeutic use)
• Hypertension (blood, drug therapy, physiopathology)
• Losartan (therapeutic use)
• Membrane Potentials (drug effects, physiology)
• Membrane Proteins (metabolism)
• Middle Aged
• Peptidyl-Dipeptidase A (blood)