Abstract | OBJECTIVE: MATERIALS AND METHODS: Seventeen patients (7 girls, 10 boys) with aneurysmal bone cysts were treated by the percutaneous approach with Ethibloc ( n=14) and histoacryl glue ( n=3) in our institution between January 1994 and June 2000. The cysts were located in the extremities ( n=6), pelvis ( n=2), spine ( n=2), mandible ( n=5), rib ( n=1) and sphenoid bone ( n=1). Percutaneous sclerotherapy was performed with fluoroscopic and/or computed tomographic guidance under general anesthesia. Clinical and imaging follow-up lasted from 24 months to 9 years and 6 months (mean: 57.3 months). The results were quantified as: excellent (residual cyst less than 20% of the initial involvement), satisfactory (residual cyst 30-50%), unsatisfactory (residual cyst more than 50%). RESULTS: The age of the patients ranged from 4 years and 6 months to 15 years and 8 months (mean: 11 years and 2 months). In nine patients, the therapeutic procedure was repeated 2-5 times. Excellent regression was observed in 16 (94%), satisfactory results in 1 (6%). There was no failure (unsatisfactory result or no response to treatment) in this reported series. The complications were minor and included: local inflammatory reaction ( n=2), small blister ( n=1), and leakage ( n=1). Relief of symptoms was achieved in all patients. No recurrence was noted during follow-up. CONCLUSION: Percutaneous sclerotherapy of aneurysmal bone cysts with Ethibloc is safe and effective. It is an important alternative to surgery, especially when surgery is technically impossible or not recommended in high-risk patients.
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Authors | Josée Dubois, Valérie Chigot, Guy Grimard, Marc Isler, Laurent Garel |
Journal | Pediatric radiology
(Pediatr Radiol)
Vol. 33
Issue 6
Pg. 365-72
(Jun 2003)
ISSN: 0301-0449 [Print] Germany |
PMID | 12768252
(Publication Type: Journal Article, Review)
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Chemical References |
- Drug Combinations
- Fatty Acids
- Propylene Glycols
- Sclerosing Solutions
- Diatrizoate
- Zein
- alcoholic prolamine solution
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Topics |
- Adolescent
- Bone Cysts, Aneurysmal
(diagnostic imaging, physiopathology, therapy)
- Child
- Child, Preschool
- Diatrizoate
(therapeutic use)
- Drug Combinations
- Fatty Acids
(therapeutic use)
- Female
- Follow-Up Studies
- Humans
- Male
- Propylene Glycols
(therapeutic use)
- Risk Assessment
- Sclerosing Solutions
(therapeutic use)
- Sclerotherapy
(methods)
- Severity of Illness Index
- Tomography, X-Ray Computed
- Treatment Outcome
- Zein
(therapeutic use)
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