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Sclerotherapy in aneurysmal bone cysts in children: a review of 17 cases.

AbstractOBJECTIVE:
To determine the efficacy of percutaneous sclerotherapy in the treatment of aneurysmal bone cysts.
MATERIALS AND METHODS:
Seventeen patients (7 girls, 10 boys) with aneurysmal bone cysts were treated by the percutaneous approach with Ethibloc ( n=14) and histoacryl glue ( n=3) in our institution between January 1994 and June 2000. The cysts were located in the extremities ( n=6), pelvis ( n=2), spine ( n=2), mandible ( n=5), rib ( n=1) and sphenoid bone ( n=1). Percutaneous sclerotherapy was performed with fluoroscopic and/or computed tomographic guidance under general anesthesia. Clinical and imaging follow-up lasted from 24 months to 9 years and 6 months (mean: 57.3 months). The results were quantified as: excellent (residual cyst less than 20% of the initial involvement), satisfactory (residual cyst 30-50%), unsatisfactory (residual cyst more than 50%).
RESULTS:
The age of the patients ranged from 4 years and 6 months to 15 years and 8 months (mean: 11 years and 2 months). In nine patients, the therapeutic procedure was repeated 2-5 times. Excellent regression was observed in 16 (94%), satisfactory results in 1 (6%). There was no failure (unsatisfactory result or no response to treatment) in this reported series. The complications were minor and included: local inflammatory reaction ( n=2), small blister ( n=1), and leakage ( n=1). Relief of symptoms was achieved in all patients. No recurrence was noted during follow-up.
CONCLUSION:
Percutaneous sclerotherapy of aneurysmal bone cysts with Ethibloc is safe and effective. It is an important alternative to surgery, especially when surgery is technically impossible or not recommended in high-risk patients.
AuthorsJosée Dubois, Valérie Chigot, Guy Grimard, Marc Isler, Laurent Garel
JournalPediatric radiology (Pediatr Radiol) Vol. 33 Issue 6 Pg. 365-72 (Jun 2003) ISSN: 0301-0449 [Print] Germany
PMID12768252 (Publication Type: Journal Article, Review)
Chemical References
  • Drug Combinations
  • Fatty Acids
  • Propylene Glycols
  • Sclerosing Solutions
  • Diatrizoate
  • Zein
  • alcoholic prolamine solution
Topics
  • Adolescent
  • Bone Cysts, Aneurysmal (diagnostic imaging, physiopathology, therapy)
  • Child
  • Child, Preschool
  • Diatrizoate (therapeutic use)
  • Drug Combinations
  • Fatty Acids (therapeutic use)
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Propylene Glycols (therapeutic use)
  • Risk Assessment
  • Sclerosing Solutions (therapeutic use)
  • Sclerotherapy (methods)
  • Severity of Illness Index
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Zein (therapeutic use)

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