Abstract |
Nitrates are old drugs, available in many formulations, that are effective in relieving symptoms in various CAD syndromes as well as congestive heart failure. Nitrate tolerance is the major problem limiting nitrate efficacy and use by physicians. Currently, an intermittent dosing strategy is the only practical way to limit the development of tolerance or attenuation of nitrate actions.
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Authors | Jonathan Abrams |
Journal | Cardiovascular drugs and therapy
(Cardiovasc Drugs Ther)
Vol. 16
Issue 6
Pg. 511-4
(Dec 2002)
ISSN: 0920-3206 [Print] United States |
PMID | 12766384
(Publication Type: Journal Article, Review)
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Chemical References |
- Nitrates
- Vasodilator Agents
- Nitroglycerin
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Topics |
- Dose-Response Relationship, Drug
- Humans
- Nitrates
(administration & dosage, adverse effects, therapeutic use)
- Nitroglycerin
(administration & dosage, adverse effects, therapeutic use)
- United States
(epidemiology)
- Vasodilator Agents
(administration & dosage, adverse effects, therapeutic use)
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