Abstract | PROBLEM: METHOD OF STUDY: We used the semi-quantitative immunofluorescent antibody assay established in our laboratory to identify the levels of IGF-II in 21 cervical cancers (seven with matching lymph nodes), 18 benign cervical biopsies, 13 endometrial cancers, 15 benign endometrial biopsies, 5 ovarian cancers, and 15 benign ovarian biopsies. RESULTS: CONCLUSION: We propose that measurement and identification of IGF-II in the cervical biopsy may be a sensitive method of detecting cervical cancer and metastatic spread in the lymph nodes.
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Authors | Subbi P Mathur, Charles P Landen, Susan M Datta, M Camille Hoffman, Rajesh S Mathur, Roger C Young |
Journal | American journal of reproductive immunology (New York, N.Y. : 1989)
(Am J Reprod Immunol)
Vol. 49
Issue 2
Pg. 113-9
(Feb 2003)
ISSN: 1046-7408 [Print] Denmark |
PMID | 12765350
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Insulin-Like Growth Factor II
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Topics |
- Endometrial Neoplasms
(metabolism)
- Female
- Fluorescent Antibody Technique
- Genital Neoplasms, Female
(metabolism)
- Humans
- Insulin-Like Growth Factor II
(metabolism)
- Lymph Nodes
(metabolism)
- Uterine Cervical Neoplasms
(metabolism)
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