Immunohistochemical characteristics of canine aortic and carotid body tumours.

Abstract

In an immunohistochemical study of 25 canine chemodectomas, 17 tumours were stained with antisera to neurone specific enolase and the same number were stained for synaptophysin; a single tumour was stained for S100. Staining for Ki-67 occurred in 18 cases; the Ki-67-labelling index and the intensity of immunostaining was increased in more pleomorphic and malignant tumours, as assessed on histological grounds. Immunohistochemistry did not aid in recognition of less well-differentiated tumours.

• Authors: P J Brown, A Rema, F Gartner
• Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine (J Vet Med A Physiol Pathol Clin Med) Vol. 50 Issue 3 Pg. 140-4 (Apr 2003) ISSN: 0931-184X [Print] Germany
• PMID: 12757551 (Publication Type: Journal Article)

Chemical References

• Ki-67 Antigen

Topics

• Animals
• Aortic Bodies
• Breeding
• Carotid Body Tumor (pathology, veterinary)
• Dog Diseases (pathology)
• Dogs
• Female
• Immunohistochemistry (veterinary)
• Ki-67 Antigen (immunology)
• Male
• Paraganglioma, Extra-Adrenal (pathology, veterinary)