| Abstract | BACKGROUND: Severe and persistent hyperemesis gravidarum is a disabling condition. Women may request termination of pregnancy because of the intolerable symptoms and stress. CASE: A woman requested termination of pregnancy because of severe hyperemesis gravidarum. Her first three pregnancies were also complicated by severe and persistent vomiting. The vomiting was successfully treated with a short course of methylprednisolone. CONCLUSION: Methylprednisolone is an effective treatment for severe hyperemesis gravidarum and should be considered for women whose vomiting is persistent and refractory to conventional therapy. |
| Authors | Louis Y Chan, Man Ho Lam, Tze Kin Lau, Robert K H Chin
(Affiliation: Departments of Obstetrics and Gynaecology, Princes of Wales Hospital, Chinese University of Hong Kong, and Princess Margaret Hospital, Shatin, Hong Kong. lyschan at cuhk.edu.hk)
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| Journal | The Journal of reproductive medicine
(J Reprod Med)
Vol. 48
Issue 4
Pg. 293-5
(Apr 2003)
ISSN: 0024-7758 United States |
| PMID | 12746996
(Publication Type: Case Reports, Journal Article)
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| Chemical References |
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| Topics |
- Adult
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Follow-Up Studies
- Humans
- Hyperemesis Gravidarum
(diagnosis, drug therapy)
- Methylprednisolone
(administration & dosage)
- Pregnancy
- Pregnancy Complications
(diagnosis, drug therapy)
- Pregnancy Outcome
- Pregnancy Trimester, First
- Severity of Illness Index
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