Successful treatment of retrograde ejaculation with amezinium.

Abstract

The effect of amezinium, a new type of antihypotensive agent, on retrograde ejaculation was evaluated in 3 patients with retrograde ejaculation. The patients received 10 mg amezinium orally once a day. All patients achieved antegrade ejaculation. Semen analyses revealed 6-50 x 10(6)/mL (mean 28.7 x 10(6)/mL) sperm with a motility of 20-50% (mean 36.7%). The wives of 2 patients became pregnant within 6 months of the initial treatment. None of the patients had any side effects. It would appear that amezinium is a useful treatment for retrograde ejaculation.

• Authors: O Ichiyanagi, I Sasagawa, Y Suzuki, S Matsuki, K Itoh, M Miura, Y Tomita
• Journal: Archives of andrology (Arch Androl) 2003 May-Jun Vol. 49 Issue 3 Pg. 215-7 ISSN: 0148-5016 [Print] England
• PMID: 12746100 (Publication Type: Journal Article)

Chemical References

• Pyridazines
• amezinium

Topics

• Adult
• Ejaculation (drug effects)
• Female
• Humans
• Male
• Pregnancy
• Pregnancy Rate
• Pyridazines (administration & dosage, pharmacology)