Abstract | OBJECTIVE: METHODS: RESULTS: The mean duration of follow-up was 4.8 +/- 0.4 yr. Treatment with estrogens resulted in a significantly lower rate of bone loss (0.002 g/cm(2)/yr +/- 0.028 vs 0.009 g/cm(2)/yr +/- 0.020, p = 0.05). Worsening cholestasis attributable to estrogen replacement therapy did not occur in any patient. One patient (2%) discontinued therapy because of side effects. CONCLUSIONS:
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Authors | K V Narayanan Menon, Paul Angulo, Gwen M Boe, Keith D Lindor |
Journal | The American journal of gastroenterology
(Am J Gastroenterol)
Vol. 98
Issue 4
Pg. 889-92
(Apr 2003)
ISSN: 0002-9270 [Print] United States |
PMID | 12738473
(Publication Type: Journal Article)
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Topics |
- Adult
- Age Factors
- Aged
- Bone Density
(drug effects)
- Cholestasis
(chemically induced)
- Cohort Studies
- Contraindications
- Estrogen Replacement Therapy
(adverse effects)
- Female
- Follow-Up Studies
- Humans
- Liver Cirrhosis, Biliary
(complications)
- Middle Aged
- Osteoporosis, Postmenopausal
(etiology, prevention & control)
- Retrospective Studies
- Severity of Illness Index
- Sex Factors
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