Anastrozole-induced remission of diaphragmatic paralysis from metastatic breast cancer treated with multiple prior therapies.

Abstract

We describe a woman with metastatic breast cancer treated with multiple rounds of prior cytotoxic and endocrine therapies, who presented with ipsilateral diaphragmatic paralysis. The use of anastrozole, a highly selective nonsteroidal aromatase inhibitor (1 mg daily), successfully induced remission of metastatic tumors in our patient, who is partially recovering from diaphragmatic paralysis.

• Authors: Takaomi Suzuma, Takeo Sakurai, Goro Yoshimura, Teiji Umemura, Yukio Shimizu, Qi-Feng Yang, Yoshitaka Okamura
• Journal: Breast cancer (Tokyo, Japan) (Breast Cancer) Vol. 10 Issue 2 Pg. 153-6 ( 2003) ISSN: 1340-6868 [Print] Japan
• PMID: 12736569 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents, Hormonal
• Nitriles
• Triazoles
• Anastrozole

Topics

• Anastrozole
• Antineoplastic Agents, Hormonal (therapeutic use)
• Breast Neoplasms (complications, drug therapy, pathology, therapy)
• Carcinoma, Ductal, Breast (complications, drug therapy, secondary, therapy)
• Combined Modality Therapy
• Female
• Humans
• Mediastinal Neoplasms (complications, drug therapy, secondary, therapy)
• Middle Aged
• Nitriles (therapeutic use)
• Remission Induction
• Respiratory Paralysis (drug therapy, etiology)
• Triazoles (therapeutic use)