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BO-653. Chugai.

Abstract
BO-653 is an antioxidant under development by Chugai for the potential treatment of atherosclerosis and the prevention of restenosis. By November 2001, BO-653 was in phase II trials for restenosis in post-percutaneous transluminal coronary angioplasty in the US, and by April 2002, the compound was in phase I trials for the same indication in Japan.
AuthorsCharles Q Meng
JournalCurrent opinion in investigational drugs (London, England : 2000) (Curr Opin Investig Drugs) Vol. 4 Issue 3 Pg. 342-6 (Mar 2003) ISSN: 1472-4472 [Print] England
PMID12735236 (Publication Type: Journal Article, Review)
Chemical References
  • 2,3-dihydro-5-hydroxy-2,2-dipentyl-4,6-di-tert-butylbenzofuran
  • Antioxidants
  • Benzofurans
Topics
  • Animals
  • Antioxidants (pharmacology, therapeutic use)
  • Arteriosclerosis (drug therapy)
  • Benzofurans (pharmacology, therapeutic use)
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Coronary Restenosis (prevention & control)
  • Humans

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