[Clinical efficacy of using ximedon in surgical practice].

Abstract

Results of clinical trial of the new pyrimidine derivative--ximedone are presented. The drug was administered per os 0.5 g x 4 times a day (0.5 h before meals). Total course dose achieved 60 g. Ximedone implementation for complex treatment of burns, trophic ulcer of lower limbs, different inflammations demonstrated positive results. Prophylaxy administration of the drug in abdominal surgery at acute appendix resulted with lower incidence of postoperative complications. High efficacy and good tolerability of the drug allows to recommend it for wide medical use.

• Authors: S G Izmaĭlov, G A Izmaĭlov, I V Zaikonnikova, V S Reznik, V Iu Tereshchenko, S M Gorbunov, G V Evranova, R Sh Shaĭmardanov, A A Muslinkin, A A Bodrov, R A Abdulkhakov, V M Lazarev, M Iu Kedrin, E A Gurylev, L Kh Mavziutov, L Kh Mavziutov, K V Malyshev, R N Gabbasov, I Z Shafikov, O S Kochnev, I V Podushkina, A G Izmaĭlov, V N Garaev, I F Sharafislamov, M Kh Gerasimova
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 47 Issue 12 Pg. 20-6 ( 2002) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Klinicheskaia éffektivnost' primeneniia ksimedona v khirurgicheskoĭ praktike.
• PMID: 12733496 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Pyrimidines
• xymedon

Topics

• Adjuvants, Immunologic (therapeutic use)
• Antibiotic Prophylaxis
• Burns (drug therapy)
• Humans
• Pyrimidines (therapeutic use)