Elastogenesis in healing wounds in bats.

Abstract

Full-thickness square wounds were made in the webs of fruit bats. Elastin was laid down in the healing scars of these wounds in two forms--as single fibers under the regenerated epidermis, and as bundles of fine fibers taking their origin and orientation from the cut ends of the web elastin bundles. This process continued over a period of 6 months, during which time other components of the scar became reduced in amount. The arrangement of the new elastin in the scar tissue was thus a replica of that seen in the normal web. There are indications in this study that elastin imparts elasticity to the scar.

• Authors: K S Bhangoo, J C Church
• Journal: Plastic and reconstructive surgery (Plast Reconstr Surg) Vol. 57 Issue 4 Pg. 468-79 (Apr 1976) ISSN: 0032-1052 [Print] United States
• PMID: 1273127 (Publication Type: Journal Article)

Chemical References

• Elastin

Topics

• Animals
• Chiroptera
• Cicatrix (pathology)
• Disease Models, Animal
• Elastin (biosynthesis, physiology)
• Regeneration
• Skin (ultrastructure)
• Skin Physiological Phenomena
• Wound Healing
• Wounds and Injuries (pathology)