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Systemic 5-fluorouracil producing an inflammatory response in porokeratosis.

Abstract
Topical 5-fluorouracil has been used as an effective treatment for porokeratosis. Upon its treatment, an inflammatory effect occurs with the topical 5-fluorouracil. We report a case of a patient with disseminated superficial actinic porokeratosis displaying a comparable inflammatory process following therapy with systemic 5-fluorouracil used to manage a metastatic breast cancer.
AuthorsW K Nahm, K G Donohue, J F Danahy, E Badiavas, V Falanga
JournalJournal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 17 Issue 2 Pg. 190-2 (Mar 2003) ISSN: 0926-9959 [Print] England
PMID12705749 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antimetabolites, Antineoplastic
  • Fluorouracil
Topics
  • Administration, Oral
  • Aged
  • Antimetabolites, Antineoplastic (administration & dosage)
  • Breast Neoplasms (drug therapy)
  • Female
  • Fluorouracil (administration & dosage)
  • Humans
  • Porokeratosis (drug therapy)

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