Abstract | PURPOSE: MATERIAL AND METHODS: Thirty consecutive patients of retinal detachment with advanced PVR were enrolled in the study. They were randomised to study and control groups (n = 15 each). Study group patients received vitreoretinal surgery with 5 IU/cc of LMWH in vitrectomy infusion fluid. The control group patients received vitroretinal surgery without heparin in the infusion fluid. Patients were followed up at 1 week, 1 month and 3 months after surgery. Postoperative bleeding, media clarity, best-corrected visual acuity and success of the surgery at the end of 3 months were compared between the two groups. RESULTS: At each follow-up visit, the study group showed a better media clarity, which was statistically significant (P = 0.0042). The study group had a 50% better chance of retinal reattachment compared to the control group. Five patients had intraoperative bleeding in the study group (33%) compared to 3 patients in the control group (20%). CONCLUSION:
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Authors | Atul Kumar, Sanjeev Nainiwal, B Sreenivas |
Journal | Indian journal of ophthalmology
(Indian J Ophthalmol)
Vol. 51
Issue 1
Pg. 67-70
(Mar 2003)
ISSN: 0301-4738 [Print] India |
PMID | 12701865
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Fibrinolytic Agents
- Heparin, Low-Molecular-Weight
- Fibrin
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Topics |
- Adult
- Aged
- Female
- Fibrin
(drug effects)
- Fibrinolytic Agents
(therapeutic use)
- Heparin, Low-Molecular-Weight
(therapeutic use)
- Humans
- Male
- Middle Aged
- Postoperative Complications
- Retinal Detachment
(surgery)
- Treatment Outcome
- Visual Acuity
- Vitrectomy
(methods)
- Vitreoretinopathy, Proliferative
(surgery)
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