Comparative study of two methods for hepatitis B antigen (HBAg) detection: double sequential counterimmunoelectrophoresis (DCIEP) and Ausria II-125I radioimmunoassay.

Abstract

Double sequential counterimmunoelectrophoresis (DCIEP) (an improved method that we have developed) and Ausria II-125I (an indirect solid-phase radioimmunoassay) were compared for HBAg detection in chronic liver diseases. 26.8% of the patients were positive using DCIEP and 41.8% were positive with Ausria II125I. The conventional counterimmunoelectrophoresis (CIEP) is less sensitive than DCIEP, the level of positive results being 18.8% (P less than 0.001)9

• Authors: J Szántay, D Dejica, O Abrudan
• Journal: Clinica chimica acta; international journal of clinical chemistry (Clin Chim Acta) Vol. 69 Issue 1 Pg. 117-9 (May 17 1976) ISSN: 0009-8981 [Print] Netherlands
• PMID: 1269148 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Hepatitis B Antigens

Topics

• Chronic Disease
• Counterimmunoelectrophoresis (methods)
• Evaluation Studies as Topic
• Hepatitis B Antigens (analysis)
• Humans
• Liver Diseases (diagnosis, immunology)
• Radioimmunoassay (methods)