HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Cutaneous and ocular habronemiasis in horses: 63 cases (1988-2002).

AbstractOBJECTIVE:
To describe clinical manifestations of cutaneous and ocular habronemiasis in horses and evaluate outcome of treatment.
DESIGN:
Retrospective study.
ANIMALS:
63 horses.
PROCEDURE:
The diagnosis was made on the basis of history, clinical signs, and identification of calcified concretions (sulfur granules) in lesions. Histologic examination of biopsy specimens was used to confirm the diagnosis. Case horses were compared with a control population of 12,720 horses examined during the same period.
RESULTS:
Arabians, gray horses, and horses with diluted coat colors were overrepresented; Thoroughbreds were underrepresented. Lesions were identified most often during the summer and early fall. The medial canthus of the eye, male genitalia, third eyelid, and distal portions of the extremities were the most commonly affected locations. Twenty-five lesions were biopsied, and results of histologic examination were consistent with a diagnosis of habronemiasis. However, nematode larvae were seen in only 11 (44%) biopsy specimens. Treatment consisted of surgical removal (7 horses) or medical treatment (56) consisting of debulking granulation tissue and topical, intralesional, or systemic treatment with corticosteroids. All horses were treated with ivermectin.
CONCLUSIONS AND CLINICAL RELEVANCE:
Results suggest that cutaneous and ocular habronemiasis should be considered when examining a horse during the summer months with a proliferative, moist, granulomatous lesion. Treatment should be aimed at decreasing the size of the lesion, reducing inflammation, and preventing recurrence. In general, the prognosis was good, and healing occurred within a few weeks. Fly control and regular deworming with ivermectin are recommended to reduce the incidence of habronemiasis.
AuthorsNicola Pusterla, Johanna L Watson, W David Wilson, Verena K Affolter, Sharon J Spier
JournalJournal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 222 Issue 7 Pg. 978-82 (Apr 01 2003) ISSN: 0003-1488 [Print] United States
PMID12685790 (Publication Type: Journal Article)
Chemical References
  • Antinematodal Agents
  • Ivermectin
Topics
  • Age Distribution
  • Animals
  • Antinematodal Agents (therapeutic use)
  • California (epidemiology)
  • Eye (parasitology, pathology)
  • Eye Infections, Parasitic (epidemiology, pathology, veterinary)
  • Female
  • Hair Color
  • Horse Diseases (epidemiology, parasitology, pathology)
  • Horses
  • Ivermectin (therapeutic use)
  • Male
  • Prognosis
  • Retrospective Studies
  • Seasons
  • Skin Diseases, Parasitic (epidemiology, pathology, veterinary)
  • Spirurida Infections (epidemiology, pathology, veterinary)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: