Management of non-neoplastic ovarian cysts with sclerotherapy.

Abstract

OBJECTIVE:

To evaluate sclerotherapy with alcohol and erythromycin in the management of simple ovarian cysts.

METHODS:

Twenty-four simple ovarian cysts were subjected to sclerotherapy with alcohol and erythromycin. All procedures were performed under local anesthesia and in an outpatient setting. Cytological examination was carried out in all cases and two patients were excluded from the study because of suspicious cytological results. The patients were followed up monthly with color Doppler sonography for more than 12 months.

RESULTS:

Cyst fluid was serous in 17 cases and dark-chocolate colored in seven cases. The volume of aspirated fluid ranged from 100 to 220 ml. The size of ovarian masses and cyst-wall thickness ranged from 5.5 to 8.5 cm and 1.5 to 5 mm, respectively. Cytological analysis of 15 cysts revealed acellular sediment, seven cysts were compatible with endometrioma, and two were reported as suspicious. During the 12-month follow-up, seven cyst recurrences were detected.

CONCLUSION:

Aspiration and sclerotherapy with alcohol and erythromycin are followed by a relatively high recurrence rate when the aspirate is bloody. However, patients with a simple cyst that is painful or liable to torsion could benefit from sclerotherapy. Such patients, who are at low risk for malignancy, are relieved with sclerotherapy while avoiding surgery.

• Authors: H Kafali, S Yurtseven, F Atmaca, I Ozardali
• Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (Int J Gynaecol Obstet) Vol. 81 Issue 1 Pg. 41-5 (Apr 2003) ISSN: 0020-7292 [Print] United States
• PMID: 12676392 (Publication Type: Journal Article)

Chemical References

• Drug Combinations
• Sclerosing Solutions
• benzoyl peroxide, erythromycin drug combination
• Erythromycin
• Benzoyl Peroxide

Topics

• Adolescent
• Adult
• Benzoyl Peroxide (therapeutic use)
• Drug Combinations
• Erythromycin (therapeutic use)
• Female
• Humans
• Ovarian Cysts (diagnostic imaging, pathology, therapy)
• Recurrence
• Sclerosing Solutions (therapeutic use)
• Sclerotherapy
• Ultrasonography, Doppler, Color