The role of
serum glutamic oxaloacetic transaminase (
SGOT) and serum
glutamic pyruvic transaminase (
SGPT) levels on intra-
abdominal injury in children has not been adequately studied. In this report, the accuracy of these tests in predicting the degree and extend of intra-abdominal and hepatic injury in children with blunt abdominal
trauma was investigated.Eighty-seven haemodynamically stable children with
multiple trauma were prospectively evaluated. The
SGOT and
SGPT of patients with and without abdominal
trauma (Groups I and II) were compared. Patients with and without radiologically verified intra-
abdominal injury were further compared (Groups Ib and Ia). There was significant difference in
SGOT and
SGPT levels of Groups I and II.
SGOT and
SGPT levels were 333.6+/-283.8 and, 197.5+/-192.5 U/l, respectively in Group Ib; but 84.2+/-55.9, 43+/-29.8 U/l in Group Ia (P<0.001). In all patients with radiologically detected intra-abdominal pathology
SGOT and
SGPT levels were above 110.5 and 63.5 U/l, respectively. In patients with hepatic injury
SGOT level was above 500 U/l and,
SGPT level was above 300 U/l. Statistically significant positive correlation was found between radiologically detected intra-abdominal pathology and increased
SGOT (above 110.5 U/l) and
SGPT (above 63.5 U/l) levels (P<0.05). These data indicated that the
SGOT and
SGPT levels were significantly higher in patients with intra-
abdominal injury even in the absence of hepatic injury. We suggest that liver function tests may be used as screening tests in children with blunt abdominal
trauma in addition to physical abdominal examination. A sudden rise up to 110.5 U/l in
SGOT and 63.5 U/l in
SGPT indicate an intra-
abdominal injury and severe hepatic injury should be suspected with higher levels of
SGOT and
SGPT.