[Efficacy of ursodeoxycholic acid in gallbladder cholesterosis accompanied by cholecystolithiasis].

Abstract

23 patients with gall-bladder cholesterosis associated with cholesterol gallstones were treated with ursodeoxycholic acid preparations. A regression of cholesterol polyps was recorded in 56.5% against the background of treatment, and complete or partial dissolution of gallstones was observed in 87%. The efficiency of dissolution of cholesterol polyps and stones in the gall-bladder went up along with the extension of the therapy terms, reaching its maximum by 7-9 months of treatment. The dissolution rates were higher for gallstones than for cholesterol polyps. The volume of bile being secreted increased, and the gall-bladder contractile function improved in the course of treatment.

• Authors: A A Il'chenko, Iu N Orlova
• Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology (Eksp Klin Gastroenterol) Issue 1 Pg. 46-50, 182 ( 2003) ISSN: 1682-8658 [Print] Russia (Federation)
• Vernacular Title: Effektivnost' ursodezoksikholevoĭ kisloty pri kholeseroze zhelchnogo pyzyria, sochetaiushchemsia s kholetsitolitiazom.
• PMID: 12664784 (Publication Type: English Abstract, Journal Article)

Chemical References

• Ursodeoxycholic Acid
• Cholesterol

Topics

• Adolescent
• Adult
• Aged
• Cholelithiasis (complications, drug therapy, metabolism)
• Cholesterol (metabolism)
• Female
• Humans
• Male
• Middle Aged
• Treatment Outcome
• Ursodeoxycholic Acid (therapeutic use)