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[Tubulo-interstitial nephritis and uveitis (TINU syndrome): a new pediatric case].

Abstract
TINU is a rare disease of unknown etiology that associates acute tubulointerstitial nephritis and uveitis in a context of systemic symptoms (asthenia, weight loss, fever) and inflammatory biological signs. We report a new case in a 10-year-old girl with unilateral uveopapillitis and renal insufficiency caused by interstitial nephritis (creatininemia: 225 micro mol/l). Complete recovery was obtained with high-dose systemic corticotherapy, with the patient remaining free of disease 2.5 years after the end of treatment. The disappearance of renal lesions was histologically verified.
AuthorsD Bensmail, I Rossignol, E Tuil, C Sabourin, Y Morin, E Héron
JournalJournal francais d'ophtalmologie (J Fr Ophtalmol) Vol. 26 Issue 2 Pg. 187-90 (Feb 2003) ISSN: 0181-5512 [Print] France
Vernacular TitleNéphropathie tubulo-interstitielle et uvéite (syndrome TINU): une nouvelle observation pédiatrique.
PMID12660595 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Anti-Inflammatory Agents
  • Prednisone
Topics
  • Anti-Inflammatory Agents (therapeutic use)
  • Child
  • Female
  • Humans
  • Nephritis, Interstitial (drug therapy)
  • Prednisone (therapeutic use)
  • Remission Induction
  • Syndrome
  • Uveitis (drug therapy)

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