Abstract |
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Authors | Stephen L Gwaltney 2nd, Stephen J O'Connor, Lissa T J Nelson, Gerard M Sullivan, Hovis Imade, Weibo Wang, Lisa Hasvold, Qun Li, Jerome Cohen, Wen-Zhen Gu, Stephen K Tahir, Joy Bauch, Kennan Marsh, Shi-Chung Ng, David J Frost, Haiying Zhang, Steve Muchmore, Clarissa G Jakob, Vincent Stoll, Charles Hutchins, Saul H Rosenberg, Hing L Sham |
Journal | Bioorganic & medicinal chemistry letters
(Bioorg Med Chem Lett)
Vol. 13
Issue 7
Pg. 1359-62
(Apr 07 2003)
ISSN: 0960-894X [Print] England |
PMID | 12657282
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
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Chemical References |
- Enzyme Inhibitors
- Pyridines
- Phenylalanine
- Histidine
- Alkyl and Aryl Transferases
- geranylgeranyltransferase type-I
- Farnesyltranstransferase
- Glycine
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Topics |
- Alkyl and Aryl Transferases
(antagonists & inhibitors)
- Biological Availability
- Crystallography, X-Ray
- Enzyme Inhibitors
(chemical synthesis, pharmacokinetics, pharmacology)
- Farnesyltranstransferase
- Genes, ras
(drug effects)
- Glycine
(analogs & derivatives, pharmacology)
- Histidine
(analogs & derivatives, pharmacology)
- Models, Molecular
- Molecular Conformation
- Phenylalanine
(analogs & derivatives, pharmacology)
- Pyridines
(chemical synthesis, pharmacology)
- Structure-Activity Relationship
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