Abstract | OBJECTIVE: to examine the effect of stent-graft deployment on pressure within an aneurysm sac and to investigate the potential sources of intra-sac pressure. MATERIAL AND METHODS: intra-sac pressure was monitored during and immediately after endovascular repair via an indwelling catheter. Intra-sac pressure was also monitored during conventional open repair and was compared with the pressure measured within patent lumbar and inferior mesenteric side-branches, both before and after restoration of iliac arterial blood flow. Intra-sac and side-branch pressures were recorded and expressed as ratios of simultaneously measured radial artery pressure. RESULTS: in the absence of a graft-related endoleak (23/25 patients), endovascular repair resulted in a significant reduction in intra-sac pulse pressure (median ratio 0.31 IQR 0.10-0.46). There was no corresponding reduction in mean intra-sac pressure (median ratio 0.91; IQR 0.83-1.00). Application of clamps at conventional open repair resulted in a fall in both intra-sac pressure (median ratio 0.39, IQR 0.32-0.64) and pressure within side-branches (median ratio 0.45, IQR 0.33-0.64). Restoration of iliac blood flow resulted in a modest recovery of the side-branch pressure (median ratio 0.63, IQR 0.57-0.81), which nonetheless remained significantly less than the intra-sac pressure recorded after EVAR (p=0.01). CONCLUSION: reperfusion of the aneurysm sac through patent side-branches seems insufficient to account for persistent pressurisation of the aneurysm after endovascular repair. This finding supports the hypothesis that pressure may be transmitted directly through stent-graft fabric.
|
Authors | S R Vallabhaneni, G L Gilling-Smith, T V How, J A Brennan, D A Gould, R G McWilliams, P L Harris |
Journal | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
(Eur J Vasc Endovasc Surg)
Vol. 25
Issue 4
Pg. 354-9
(Apr 2003)
ISSN: 1078-5884 [Print] England |
PMID | 12651175
(Publication Type: Clinical Trial, Journal Article)
|
Topics |
- Aortic Aneurysm
(physiopathology, surgery)
- Aortic Rupture
(etiology, physiopathology)
- Blood Pressure
(physiology)
- Blood Vessel Prosthesis Implantation
(adverse effects)
- Catheters, Indwelling
(adverse effects)
- Coronary Circulation
(physiology)
- Hemodynamics
(physiology)
- Humans
- Postoperative Complications
- Prosthesis Failure
- Vascular Patency
(physiology)
|